The potential impact of the 13-valent conjugate pneumococcal vaccine on antibiotic resistance in pneumococci

Abstract

The emergence of antibiotic-resistant Streptococcus pneumoniae strains is primarily due to a selection of resistant strains by antibiotic use. The majority of antibiotic-resistant pneumococcal strains exist as a limited number of serotypes, many of which are already included in a 7-valent pneumococcal conjugate vaccine (PCV7).