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Antimicrobial Susceptibility Patterns of Selected Bacteraemic Isolates from South African Public Sector Hospitals, 2010
DOI:
10.1080/10158782.2011.11441461
Author(s):
C BamfordNational Health Laboratory Service (NHLS), Groote Schuur and University of Cape Town, , K BonorchisNational Health Laboratory Service (NHLS), Green Point and University of Cape Town, , A RyanNational Health Laboratory Service (NHLS), Green Point and University of Cape Town, , J SimpsonNational Health Laboratory Service (NHLS), Green Point and University of Cape Town, , E ElliottNational Health Laboratory Service (NHLS), Universitas and University of the Free State, , R HoffmannNational Health Laboratory Service (NHLS), Tygerberg and Stellenbosch University, , P NaickerNational Health Laboratory Service (NHLS), Tygerberg and Stellenbosch University, , N IsmailNational Health Laboratory Service (NHLS), Steve Biko Academic and University of Pretoria, , N MbelleNational Health Laboratory Service (NHLS), Dr George Mukhari and University of Limpopo, , M NchabelengNational Health Laboratory Service (NHLS), Dr George Mukhari and University of Limpopo, , T NanaNational Health Laboratory Service (NHLS), Charlotte Maxeke Johannesburg Academic and University of the Witwatersrand, , C SriruttanNational Health Laboratory Service (NHLS), Charlotte Maxeke Johannesburg Academic and University of the Witwatersrand, , S SeetharamNational Health Laboratory Service (NHLS), Chris Hani Baragwanath and University of the Witwatersrand, , J WadulaNational Health Laboratory Service (NHLS), Chris Hani Baragwanath and University of the Witwatersrand, ,
Abstract
We report on antimicrobial susceptibility surveillance data for six key bloodstream pathogens (Escherichia coli, Klebsiella pneumoniae, Enterobacter spp., Pseudomonas aeruginosa, Acinetobacter baumannii and Staphylococcus aureus) identified in public sector hospitals in South Africa during 2010. Major findings include the accelerated emergence of carbapenem resistance among K. pneumoniae and Enterobacter species, with overall susceptibility rates of 98% and 96% for ertapenem, and above 99% for meropenem and imipenem. Levels of resistance among P. aeruginosa and A. baumannii remain high in all centres, with few changes since 2009. Large decreases in piperacillin-tazobactam susceptibility rates were noted at three institutions, probably related to methodological issues. S. aureus remains a major pathogen countrywide, with between 30-60% of isolates resistant to cloxacillin [methicillin-resistant S. aureus (MRSA)]. Ongoing surveillance for antimicrobial resistance is vital, and the use of a centralised data extraction system may aid in this.
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