The expression status of human epidermal growth factor receptor 2 in epithelial ovarian cancer in Ibadan, Nigeria

Abstract

Background: It has been proposed that the overexpression of the human epidermal growth factor receptor 2 (HER2/neu proto-oncogene) could be a possible therapeutic target in epithelial ovarian cancer, as has been the case in breast carcinomas. However, there is lack of knowledge on the status of the gene in neoplasms which occur in black women. The objective of this study was to determine HER2/neu expression status in EOC in black women.